Argireline® + Matrixyl® 3000 Serum – For Fine Lines & Expression Lines | Smooth & Firm Looking Skin | 30ml

10% Argireline (Acetyl Hexapeptide-8)

A targeted peptide that helps reduce the appearance of dynamic expression lines, especially across the forehead and around the eyes.

5% Matrixyl 3000 (Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7)

A clinically recognised peptide duo that supports collagen and elastin appearance for smoother, firmer-looking skin.

8% Hydration Complex

Hyaluronic Acid + Tremella Mushroom work together to plump, smooth and deeply hydrate the skin.

Apply 2–3 drops to clean, slightly damp skin.

Gently smooth over face, focusing on areas of expression lines.

Follow with moisturiser.
Use morning and/or evening.

🌾 Oat Peptide – helps calm and support the skin barrier
🌿 Botanical Extract Complex – antioxidant-rich plant extracts including wild mint, golden chamomile, aloe vera, purslane and sophora root
🌼 Panthenol (Pro-Vitamin B5) – supports barrier function and softness

Pair seamlessly with our Copper Peptide Serum for enhanced peptide support, while remaining highly effective as a standalone treatment.

How to Layer:

Option 1 (Peptide Power Routine)
Cleanse → Argireline + Matrixyl Serum → Copper Peptide Serum → Moisturiser

Option 2 (Alternate Routine)
Morning: Argireline + Matrixyl
Evening: Copper Peptide

Argireline targets expression lines.
Matrixyl supports collagen appearance.
Copper Peptides support repair and skin resilience.

Together, they create a complete peptide system.

• Fine lines & early signs of ageing
• Forehead lines & crow’s feet
• Loss of firmness
• Dehydrated skin
• Those building a peptide-focused routine

Suitable for most skin types, including sensitive.

Lightweight. Fragrance-free. Designed to layer beautifully — including with our Copper Peptide Serum.

Vegan-friendly. Cruelty-free.

Texture & Feel

Lightweight gel-serum
Absorbs quickly
No stickiness
No pilling
Makeup-friendly
Fragrance-free

Full Ingredients (INCI)

Aqua, Acetyl Hexapeptide-8*, Sodium Hyaluronate, Propanediol, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7**, Plant Extract Complex (Mentha Arvensis Leaf Extract, Chrysanthellum Indicum Extract, Portulaca Oleracea Extract, Aloe Barbadensis Extract, Sophora Flavescens Root Extract, Pelargonium Graveolens Extract), Glyceryl Glucoside, Corn Gluten Amino Acids, Yeast Ferment Extract, Avena Sativa Peptide, Saccharide Isomerate, Glycerin, Panthenol, Hexylene Glycol, Hydroxyacetophenone, Xanthan Gum, Tremella Fuciformis Polysaccharide

*Argireline
**Matrixyl 3000

Size: 30ml
PAO: 6 Months
Vegan-Friendly
Cruelty-Free
Fragrance-Free
Small Batch Formulated

Argireline® is a registered trademark of Lipotec S.A.U. (a subsidiary of Lubrizol Advanced Materials, Inc.). Matrixyl® 3000 is a registered trademark of Sederma Inc. (a subsidiary of Croda International Plc).Sapónne Naturals is not affiliated with, endorsed by, or sponsored by these companies.

We currently ship to the UK, USA, Switzerland, Canada, Norway, the Netherlands, New Zealand, Italy, France and Australia

Order processing takes 1–3 working days. Once your order is dispatched, you’ll receive an email with a tracking number. 

UK: We use Royal Mail Tracked 48 for all UK orders. Shipping starts from £3.99 depending on weight, and is free for orders over £28.

Deliveries typically arrive within 2–5 business days, but please allow extra time during busy periods as processing and delivery may take longer.

USA: For international orders to the USA, shipping costs between £11-£33 based on parcel weight, calculated at checkout. 

Italy, Switzerland & Ireland: Deliveries are handled by Royal Mail International Tracked, taking 3-7 business days with shipping fees ranging from £5.95 to £20. Bulk orders can be arranged via email.

Canada, France, Netherlands, Norway, New Zealand, and Australia: We use International Tracked via Royal Mail for these destinations, with shipping fees starting at £7 and varying based on the parcel's weight. Expect delivery within 3-7 business days.

Please note that customers are responsible for any customs or import taxes imposed by the destination country.